vit-5 RNAi

Species: Nematode (Taxid: 6239)
Factor: vit-5
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference against vit-5 extends mean lifespan by 10-22%. vit-5 is differentially transcribed in daf-16 and daf-2 RNAi animals [12845331]. RNAi knockdown of vit-5 starting at hatching or only during the adulthood significantly extends lifespan of wild-type, but does not alter, or even shortens the lifespan of eat-2 mutants [22810224].

Mean: +10 to +22

References:
  • 12845331: Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



  • Edit / Update (Admin) | Delete

    Comment on This Data Unit