rrf-1 mutation

Species: Nematode (Taxid: 6239)
Factor: rrf-1
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Although rrf-1(pk1417) mutants seem to have elevated DAF-16 activity (as sod-3 transcript level is increased) the mean and maximum lifespan or ability to withstand elevated temperature is not different from wild-type [22574120].


References:
  • 22574120: C. elegans rrf-1 mutations maintain RNAi efficiency in the soma in addition to the germline.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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