acs-4 RNAi

Species: Nematode (Taxid: 6239)
Factor:
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Knockdown of acs-4 via RNAi started after the animal reached the late L4 stage appeared not significant affect on lifespan (although there was a slight non-significant increase by 5% in mean lifespan). However the same study found also a significant increase in mean lifespan by 6-9% in further experiments [22103665].

Mean: +5 to 9%

References:
  • 22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.




  • Edit / Update (Admin) | Delete

    Comment on This Data Unit