D2030.4 RNAi

Species: Nematode (Taxid: 6239)
Factor: D2030.4
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNAi against D2030.4 prolongs mean and maximum lifespan by 43% and 50%, respectively. Lifespan extension by RNAi of D2030.4 is not suppressed by daf-16. D2030.4 RNAi animals have lower ATP content and oxygen consumption [12447374].

Mean: +43
Maximum: +50

References:
  • 12447374: A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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