daf-2 RNAi

Species: Nematode (Taxid: 6239)
Factor: daf-2
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNAi against daf-2 extends mean and maximum lifespan by 47 and 65% [12471266]. daf-2 RNAi icreases mean lifesapn by 89% [18828672].

Mean: +47 to +89
Maximum: +65

References:
  • 12471266: Rates of behavior and aging specified by mitochondrial function during development.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
  • Comparisons:
  • daf-2 RNAi vs. control : <0.0001(p-value)
  • daf-2 RNAi vs. control : <0.0001(p-value)
  • wild-type RNAi vs. wild-type ( 20°C ) : 61.1(mean) 47.8(max)
  • wild-type RNAi vs. wild-type ( 20°C ) : 73.7(mean) 42.9(max)



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