Constitutive miR-277 expression

Species: Fruit fly (Taxid: 7227)
Factor: mir-277
Manipulation: Gain-of-Function, Overexpression

Constitutive miR-277 expression shortens lifespan and synthetically lethal with reduced insulin signaling, indicating that metabolic control underlies this phenotype [23669073].

  • 23669073: Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan.

  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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