MTF-1 overexpression

Species: Fruit fly
Factor: MTF-1
Manipulation: Gain-of-Function, Overexpression

MTF-1 overexpression in either the peripheral nervous system or motorneurons extends both mean and maximum lifespan by 40% in males [18775584].

Mean: +40
Maximum: +40

  • 18775584: Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity.

  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Edit / Update (Admin) | Delete

    Comment on This Data Unit