Denigma

LBR overexpression

Species: Fruit fly (Taxid: 7227)
Factor: LBR
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of Lamin B receptor in the adult muscle and in the abdominal fat body results in a 54% and 46% reduction of mean lifespan, respectively [18494863].


References:
  • 18494863: The farnesylated nuclear proteins KUGELKERN and LAMIN B promote aging-like phenotypes in Drosophila flies.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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