Akt1 RNAi

Species: Fruit fly (Taxid: 7227)
Factor: Akt1
Manipulation: Loss-of-Function, Knockdown, RNA Interference

RNA interference of Akt1 in intestinal stem cells, results in impaired regeneration of the intestinal epithelium and a short lifespan. In males and females on mean lifespan is 11.4% and 7.4% lower [20976250].

Mean: -11.4 to -7.4

  • 20976250: Lifespan extension by preserving proliferative homeostasis in Drosophila.

  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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