Drd4 knockout

Species: House mouse (Taxid: 10090)
Factor: Drd4
Manipulation: Loss-of-Function, Knockout, Mutation

Drd4 knockout mice, when compared with wild-type and heterozygous mice, display a 7 - 9.7% decrease in lifespan, reduced spontaneous locomotor activity, and no lifespan increase when reared in an enriched environment [23283341].

Mean: -7 to -9.7

  • 23283341: DRD4 Genotype Predicts Longevity in Mouse and Human.

  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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