Efemp1 knockout

Species: House mouse (Taxid: 10090)
Factor: Efemp1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion

Efemp1 knockout mice exhibited an early onset of aging-associated phenotypes including a 20% shorted median lifespan and 30% shorter maximum lifespan, decreased body mass, lordokyphosis, reduced hair growth, and atrophy [17872905].

Median: +20
Maximum: +30

  • 17872905: Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice.

  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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