Denigma

Casp-2 deficiency

Species: House mouse (Taxid: 10090)
Factor: Casp2
Manipulation: Loss-of-Function, Mutation, Deletion
Effect:

Loss of caspase-2 resulted in a shortened (10%) maximum lifespan and in enhanced aging-related traits such as impaired hair growth, increased bone loss, and reduced body fat content [17188333].

Maximum: -10

References:
  • 17188333: Caspase-2 deficiency enhances aging-related traits in mice.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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