2-ME treatment

Species: House mouse (Taxid: 10090)
Factor: 2-ME
Manipulation: Diet Intervention, Drug treatment
Effect:

Animals fed a diet supplemented with 2-mercaptoethanol (2-ME) exhibit an increased mean and maximum lifespan [6334792].

T-cell-dependent immune responses are higher in the 2-ME-fed mice compared to the controls when the animals are young. The accumulation of fluorescent products of lipid peroxidation damage is also delayed in the lymphocytes of the 2-ME-fed mice and tumor onset and incidence is reduced in these animals [6334792].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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