Denigma

Metformin treatment

Species: Norway rat (Taxid: 10116)
Factor: Met
Manipulation: Diet Intervention, Drug treatment
Effect:

In rats metformine treatment reduces body weight significantly (despite similar food intake) but fails to significantly extend the lifespan at any quantile (25th, 50th, 75th, or 90th), overall or maximum lifespan (p > 0.05) [20304770].


References:
  • 20304770: Metformin supplementation and life span in Fischer-344 rats.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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