Minocycline treatment

Species: Fruit fly (Taxid: 7227)
Factor:
Manipulation: Diet Intervention, Drug treatment
Effect:

Treatment with minocycline (0.87mM) prolongs mean, median and maximum lifespan of wild-type (Oregon strain) of both genders. In females mincocycline extend mean and maximum lifespan by 57 and 78%, respectively. In males minocycline results in a mean and maximum lifespan extension by 114 and 28%, respectively [23185716].

Mean: +57.1 to +114.3
Maximum: +28.1 to +78.3

References:
  • 23185716: Minocycline effect on life and health span of Drosophila melanogaster.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
  • Comparisons:
  • None vs. None ( female ) : 57.1(mean) 78.3(max) <0.0001(p-value)
  • None vs. None ( male ) : 114.3(mean) 28.1(max) <0.0002(p-value)



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