Denigma

HAC1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: HAC1
Manipulation: Loss-of-Function, Mutation, Deletion
Effect:

Deletion of HAC1 decreases mean, median and maximum replicative lifespan by 10, 8 and 5%, respectively [23167605].

Mean: +10.3
Median: +8.3
Maximum: +5.3

References:
  • 23167605: Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
    • Comparisons:
  • hac1 vs. wild-type ( 30°C ) : 10.3(mean) 8.3(median) 5.3(max)

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