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    Denigma » Lifespan > Interventions > g mutation o Interventions | Add / Create | Archive
    • Mouse Lifespan Experiments (Hide)

g mutation

Species: Fruit fly (Taxid: 7227)
Factor: g
Manipulation: Loss-of-Function, Mutation
Effect:

Loss-of-function mutation reduces mean lifespan by 11 - 42% and maximum lifespan by 7 - 30% [17435236].

Mean: -11 to -42
Maximum: -7 to -30

References:
  • 17435236: Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
  • Comparisons:
  • garnet vs. Canton-S ( 25°C male ) : -41.5(mean) -33.8(max) <0.0001(p-value)
  • garnet vs. white1118 ( 29°C male ) : -10.9(mean) -6.9(max) 0.0194(p-value)



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