Denigma

fbxa-121 RNAi

Species: Nematode (Taxid: 6239)
Factor: fbxa-121
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference of fbxa-121 in adulthood shortens the extended lifespan of daf-2(mu150) mutants. Only a negligible or small reduction in the lifespan of wild-type worms was observed in knockouts [17392428].


References:
  • 17392428: Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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