Denigma

SIR-2.4 overexpression

Species: Nematode (Taxid: 6239)
Factor: sir-2.4
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of SIR-2.4 does not change the mean or maximum lifespan of wild-type nor the ncreased lifespan of daf-2(e1370) mutants [Tishkoff et al. 2012].


References:
  • 23028355: C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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