Denigma

aak-2 overexpression

Species: Nematode (Taxid: 6239)
Factor: aak-2
Manipulation: Gain-of-Function, Overexpression
Effect:

Transgenic animals with a higher aak-2 gene dose live on average 13% longer with a maximum lifespan extension on up to 25% [15574588].

Mean: +13
Maximum: +25

References:
  • 15574588: The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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