hpd-1 RNAi

Species: Nematode (Taxid: 6239)
Factor: hpd-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNAi knockdown of hpd-1 starting at hatching or only during the adulthood significantly extends lifespan of both wild-type and eat-2. In wild-type mean, 75%ile, and maximum lifespan of wild-type is increased by 20-22%, 18-35%, and 10%. In eat-2 mutants mean, 75%ile and maximum lifespan is enhanced by 7-16%, 5-19%, and 17% [22810224].

Mean: +20 to +22
Maximum: +10

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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