rps-14 RNAi

Species: Nematode (Taxid: 6239)
Factor: rps-14
Manipulation: Loss-of-Function, Knockdown, RNA Interference

rps-14 RNAi in the adulthood extends mean and maximum lifespan by 17 and 22% [23144747]. Knockdown of rps-14 via RNAi started after the animal reached the late L4 stage extends lifespan by 6-19% [22103665].

Mean: +6 to +19
Maximum: +21.7

  • 22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.
  • 23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.

  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
  • Comparisons:
  • F37C12.9 RNAi vs. N2 Bristol : 16.6(mean) 21.7(max)

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