Denigma

MXR2 deletion

Species: Budding yeast (Taxid: 4932)
Factor: MXR2
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of MXR2 (alias MsrB) has no effect on replicative lifespan under normal growth conditions, but simulatonous deletion of MXR2 together with MXR1 dramatically reduces replicative lifespan by 63% [15141092].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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