MXR1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: MXR1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of MXR1 (alias MsrA) decreases (by 25%) the replicative lifespan [15141092]. Deletion of MXR1 decreases replicative lifespan [19049972]. MXR1 deletion decreases replicative lifespan on either glucose or lactate as carbon source [20799725]. Although deletion or overexpression of MXR2 (alias MsrB) has no effect under normal growth conditions, the simultaneous deletion of MXR1 and MXR2 reduces the lifespan by 63% [15141092].

Mean: -25

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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