Denigma

MAPK1 overexpression

Species: Budding yeast (Taxid: 4932)
Factor: MAPK1
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of human MAPK1 (alias ERK2) confers resistance to heat shock and oxidative stress extends median chronological lifespan by 24% and was statistically non-addative with cyr1-1 mutation [17662940].

Median: +24

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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