CLN3 overexpression

Species: Budding yeast (Taxid: 4932)
Factor: CLN3
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression shortens chronological lifespan together with age-dependent increases in genome instability and apoptosis. While around 80% of wild-type cells are alive almost non CLN3 overexpressers are alive (under condition that avoids adaptive regrowth) [17710147].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



  • Edit / Update (Admin) | Delete

    Comment on This Data Unit