Denigma

let-4 RNAi

Species: Nematode (Taxid: 6239)
Factor: let-4
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA intereference of let-4 extends mean and 75%ile lifespan by 4%, but reduces maximum lifespan by 25% [22768380].

Mean: +4
Maximum: -25

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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