glc-4 RNAi

Species: Nematode (Taxid: 6239)
Factor: glc-4
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference of glc-4 extends lifespan on NGM agar covered with killed or live bacteria as well as in liquid culture medium. glc-4 RNAi extends the mean, 75%ile, and maximum lifespan by 13, 11, and 19%. glc-4(JD31) increases the mean, 75%ile, and maximum lifespan by 13-23, 11-23, 19-34% [22768380].

RNAi of glc-4 suppresses pheromone-induced dauer formation [22768380].

Mean: +13 to 23
Maximum: +19 to + 34

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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