Denigma: Intervention

gar-3 RNAi

Species: Nematode (Taxid: 6239)
Factor: gar-3
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference of gar-3 extends lifespan on NGM agar covered with killed or live bacteria as well as in liquid culture medium. gar-3 RNAi extends mean, 75%ile, and maximum lifespan by 11, 14 an 17%. RNAi inactivation of gar-3 reduces Q35 aggregation [22768380].

Mean: +11
Maximum: +17

Aging Relevance Analysis/Source:

GenAge