Denigma

ERG5 deletion

Species: Budding yeast (Taxid: 4932)
Factor: ERG5
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of ERG5 decreases replicative lifespan by 35% in the a strain [18340043], but increases mean chronological lifespan by 26 - 116% (26, 40, 43, 62, 116) in diploid cells [21447998]. Deletion of ERG5 cancels out the replicative lifespan extension of 0.5% glucose restriction [18690010].

Mean: -35 to +116

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Edit / Update (Admin) | Delete

    Comment on This Data Unit