Denigma

YHB1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: YHB4
Manipulation: Loss-of-Function, Knockout, RNA Interference, Deletion
Effect:

Deleting YHB1 partially abolished DR-induced replicative lifespan extension, whereas deleting SFA1 alone had no effect. sfa1;yhb1 double mutant cancels out the ability of moderate DR to extend replicative lifespan, but not chronological lifespan. Yhb1 and Sfa1 may play redundant roles [21584246].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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