Denigma

GUP1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: GUP1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

GUP1 deletion extends mean and maximum replicative lifespan by 32 and 30%, respectively, as well as chronological lifespan. DR-induced maximal replicative lifespan extension is not further increased by GUP1 deletion, while gup1 mutant displayed longer chronological lifespan under DR [21584246].

Mean: +32
Maximum: +30

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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