Denigma

gpa2 constitutive active mutation

Species: Fission yeast (Taxid: 4896)
Factor: gpa2
Manipulation: Gain-of-Function, Mutation
Effect:

Constitutive active mutation of gpa2 (alias git8) decreases chronological lifespan under AL (2% glucose) and almost completely cancels out the lifespan extending effect of DR (0.2% glucose) [19266076].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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