CG7834 knockdown

Species: Fruit fly (Taxid: 7227)
Factor: CG7834
Manipulation: Loss-of-Function, Knockdown, RNA Interference

Muscle specific RNAi knockdown of CG7834 which reduces its mRNA levels by 25-35%, significantly reduces the DR-dependent lifespan extension. CG7834 RNAi animals exhibit only a 14% increase compared to the 55% lifespan-increase in controls upon DR [22768842].

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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