sem-5

Symbol: sem-5
Name: SEx Muscle abnormal
Entrez gene ID: 181055
Ensembl gene ID: C14F5.5
Species: Worm (Taxid: 6239)

Functional description:
Regulates RAS-MAP and -IP3 signal transduction; Acts both in vulval induction and sex myoblast migration. Presumably interacts with the kinase receptor let-23 and with a target that modifies the Ras-like protein let-60. [UniProt]

Observation:

RNA interference in adulthood increased mean lifespan by 24%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • GRB2 (9606)
  • GRB2 (9598)
  • GRB2 (9615)
  • GRB2 (9913)
  • Grb2 (10090)
  • Grb2 (10116)
  • GRB2 (9031)
  • grb2 (7955)
  • drk (7227)
  • AgaP_AGAP011768 (7165)
  • sem-5 (6239)



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