Symbol: rps-14
Name: Ribosomal Protein, Small subunit
Alias: Ribosomal Protein;Small subunit family member (rps-14);WBGENE00004483
Entrez gene ID: 176006
Ensembl gene ID: F37C12.9
Species: Worm
(Taxid: 6239)
Functional description:
Protein RPS-14; 40S ribosomal protein S14 [Source:UniProtKB/Swiss-Prot;Acc:P48150] [Ensembl]
Observation:
rps-14 RNAi in the adulthood extends mean and maximum lifespan by 17 and 22% [23144747]. Knockdown of rps-14 via RNAi started after the animal reached the late L4 stage extends lifespan by 6-19% [22103665].
Interventions:
rps-14 RNAi
+6 to +19%
+21.7%
Assays:
Organismal Lifespan
Mean: +6 to +19
Maximum: +22
Classification:
Gerontogene
Positive Gerontogene
References:
22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.
23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.
Aging Relevance Analysis/Source:
GenAge
GenDR
Homologs
RPS14
(9606)
RPS14
(9615)
RPS14
(9913)
Rps14
(10090)
Rps14
(10116)
RPS14
(9031)
rps14
(7955)
RpS14a
(7227)
RpS14b
(7227)
AgaP_AGAP000655
(7165)
AgaP_AGAP002346
(7165)
rps-14
(6239)
rps1401
(4896)
rps1401
(4896)
RPS14B
(4932)
RPS14A
(4932)
KLLA0B07623g
(28985)
AGOS_AEL152W
(33169)
GeneID:2675440
(148305)
NCU07830
(5141)
AT3G11510
(3702)
AT2G36160
(3702)
AT3G52580
(3702)
Os02g0162500
(4530)
Os04g0413600
(4530)
Os02g0534800
(4530)
PFE0810c
(5833)
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