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Symbol: par-6 Name: Partitioning defective protein 6 Alias: Partitioning defective protein 6; abnormal embryonic PARtitioning of cytoplasm family member (par-6);WBGENE00003921 Entrez gene ID: 173137 Ensembl gene ID: T26E3.3 Species: Worm (Taxid: 6239) Functional description: abnormal embryonic PARtitioning of cytoplasm ; Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. [UniProt] Observation: par-6 RNAi in the adulthood extends the lifespan [New longevity regulators]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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