TRM9

Symbol: TRM9
Name: TRna Methyltransferase 9
Alias: KTI1
Entrez gene ID: 854994
Ensembl gene ID: YML014W
Species: Yeast (Taxid: 4932)

Functional description:
Trm9p; tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNA(Arg3) and tRNA(Glu), likely as part of a complex with Trm112p; deletion confers resistance to zymocin [Source:SGD;Acc:S000004476] [Ensembl]

Observation:

TRM9 deletion almost triples mean chronological lifespan under starvation/extreme DR, increases heat resistance, but reduces resistance to acetic acid. Similar effect were present in the BY746 background in SDC medium [20657825].



Interventions:
  • TRM9 deletion

  • Assays: Chronological Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ALKBH8 (9606)
  • ALKBH8 (9598)
  • ALKBH8 (9615)
  • ALKBH8 (9913)
  • Alkbh8 (10090)
  • Alkbh8 (10116)
  • ALKBH8 (9031)
  • LOC556362 (7955)
  • CG17807 (7227)
  • AgaP_AGAP011900 (7165)
  • C14B1.10 (6239)
  • trm9 (4896)
  • TRM9 (4932)
  • KLLA0B01023g (28985)
  • GeneID:5049319 (148305)
  • NCU01705 (5141)
  • AT1G36310 (3702)
  • Os02g0750500 (4530)



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