MDH2

Symbol: MDH2
Name: Cytoplasmic malate dehydrogenase, one of the three isozymes that catalyze interconversion of malate and oxaloacetate; involved in gluconeogenesis during growth on ethanol or acetate as carbon source; interacts with Pck1p and Fbp1pphosphorylated
Entrez gene ID: 853994
Species: Yeast (Taxid: 4932)

Functional description:
Mdh2p; Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1 [Source:SGD;Acc:S000005486] [Ensembl]

Observation:

Replicative lifespan increased by 15%



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • MDH2 (4932)
  • KLLA0E07525g (28985)
  • AGOS_ADL164C (33169)



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