cct-4

Symbol: cct-4
Name: Chaperonin Containing TCP-1 4
Entrez gene ID: 174330
Ensembl gene ID: K01C8.10
Species: Worm (Taxid: 6239)

Functional description:
assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. [UniProt]

Observation:

RNA interference of cct-4 in adulthood results in a 28% increase in mean lifespan [17411345].



Interventions:
  • cct-4 RNAi +28%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CCT4 (9606)
  • CCT4 (9598)
  • CCT4 (9615)
  • CCT4 (9913)
  • Cct4 (10090)
  • Cct4 (10116)
  • CCT4 (9031)
  • cct4 (7955)
  • CG5525 (7227)
  • AgaP_AGAP009505 (7165)
  • cct-4 (6239)
  • cct4 (4896)
  • CCT4 (4932)
  • KLLA0F05005g (28985)
  • AGOS_ADR083W (33169)
  • GeneID:2679296 (148305)
  • NCU02839 (5141)
  • AT3G18190 (3702)
  • Os10g0514600 (4530)
  • Os02g0332200 (4530)
  • MAL13P1.283 (5833)



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