INP54

Symbol: INP54
Name: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
Entrez gene ID: 854089
Species: Yeast (Taxid: 4932)

Functional description:
Inp54p; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins [Source:SGD;Acc:S000005426] [Ensembl]

Observation:

Replicative lifespan increased by 15% in the alpha strain and decreased by 15% in the a strain



Interventions:
  • INP54 deletion -15 to +30%

  • Assays: Replicative Lifespan

    Classification:
  • Aging Associated


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • INP54 (4932)
  • KLLA0F24772g (28985)
  • AGOS_AEL090C (33169)



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