INP51

Symbol: INP51
Name: INositol polyphosphate 5-Phosphatase 51
Entrez gene ID: 854815
Ensembl gene ID: YIL002C
Species: Yeast (Taxid: 4932)

Functional description:
Inp51p; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth [Source:SGD;Acc:S000001264] [Ensembl]

Observation:

Deletion of INP51 increases replicative lifespan by 10% in the alpha strain and in a strain [18340043; 19030232].



Interventions:
  • INP51 deletion +10%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • INP51 (4932)
  • KLLA0D13860g (28985)
  • AGOS_ADL002C (33169)



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