Symbol: GCN4 Name: Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels Entrez gene ID: 856709 Species: Yeast (Taxid: 4932) Functional description: Gcn4p; Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels [Source:SGD;Acc:S000000735] [Ensembl] Observation: Deletion of GCN4 increases the replicative lifespan by 10% in the alpha strain [19030232]. GCN4 deletion decreases the lifespan in the alpha and a strain [20657825]. The chronological lifespan of GCN4 deletion is strongly decreased in the a strain [20421943]. Interventions: Assays: Replicative Lifespan Chronological Lifespan Classification: Type: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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