DUN1

Symbol: DUN1
Name: Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair
Entrez gene ID: 851457
Species: Yeast (Taxid: 4932)

Functional description:
Dun1p; Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair [Source:SGD;Acc:S000002259] [Ensembl]

Observation:

Replicative lifespan decreased by 25% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • DUN1 (4932)
  • KLLA0E01584g (28985)
  • AGOS_AFL188C (33169)



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