CYT2

Symbol: CYT2
Alias: CC1HL; cytochrome c1 heme lyase
Entrez gene ID: 853775
Ensembl gene ID: YKL087C
Species: Yeast (Taxid: 4932)

Functional description:
Cyt2p; Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1 [Source:SGD;Acc:S000001570] [Ensembl]

Observation:

Mutation of CYT2 decreases replicative lifespan by 25% in the alpha strain [18340043; 19030232].



Interventions:
  • CYT2 mutation -25%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • HCCS (9606)
  • LOC465489 (9598)
  • LOC480834 (9615)
  • HCCS (9913)
  • Hccs (10090)
  • Hccs (10116)
  • HCCS (9031)
  • hccs (7955)
  • SPAC24C9.02c (4896)
  • CYT2 (4932)
  • KLLA0F25894g (28985)
  • AGOS_ADR154W (33169)
  • GeneID:2680747 (148305)
  • NCU08138 (5141)



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