Denigma

CYC3

Symbol: CYC3
Name: Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)
Entrez gene ID: 851192
Species: Yeast (Taxid: 4932)

Functional description:
Cyc3p; Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS) [Source:SGD;Acc:S000000037] [Ensembl]

Observation:

Replicative lifespan decreased by 20% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • hccsa (7955)
  • Cchl (7227)
  • AgaP_AGAP003843 (7165)
  • cchl-1 (6239)
  • SPBC26H8.12 (4896)
  • CYC3 (4932)
  • KLLA0C13123g (28985)
  • AGOS_ADR382W (33169)
  • GeneID:2676111 (148305)
  • NCU05601 (5141)
  • PFL1185c (5833)



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