Denigma: Factor

BAS1

Symbol: BAS1
Name: BASal 1
Entrez gene ID: 853974
Ensembl gene ID: YKR099W
Species: Yeast (Taxid: 4932)

Functional description:
Bas1p; Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes [Source:SGD;Acc:S000001807] [Ensembl]

Observation:

Deletion of BAS1 increases replicative lifespan by 30% in the alpha strain [16293764; 19030232].

Interventions:

BAS1 deletion +30%

Assays: Replicative Lifespan

Classification:

Gerontogene

Positive Gerontogene

Aging Relevance Analysis/Source:

GenAge