ACS2

Symbol: ACS2
Name: Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions
Entrez gene ID: 850846
Species: Yeast (Taxid: 4932)

Functional description:
Acs2p; Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions [Source:SGD;Acc:S000004143] [Ensembl]

Observation:

Replicative lifespan decreased by 70% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • LOC423347 (9031)
  • SPCC191.02c (4896)
  • ACS2 (4932)
  • KLLA0D17336g (28985)
  • AGOS_AGL148C (33169)
  • GeneID:2676505 (148305)
  • NCU06836 (5141)
  • PFF1350c (5833)



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