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Symbol: ACO2 Name: ACOnitase 2 Entrez gene ID: 853230 Ensembl gene ID: YJL200C Species: Yeast (Taxid: 4932) Functional description: Aco2p; Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol [Source:SGD;Acc:S000003736] [Ensembl] Observation: Deletion of ACO2 increases replicative lifespan by 20% in the alpha strain and decreases it by 10% in the a strain [18340043]. Its deletion increases mean chronological lifespan by 6 - 44% (6, 22, 20, 20, 19, 44) in diploid cells [21447998]. Assays: Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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