Denigma: Factor

ABP1

Symbol: ABP1
Name: Actin Binding Protein 1
Entrez gene ID: 850450
Ensembl gene ID: YCR088W
Species: Yeast (Taxid: 4932)

Functional description:
Abp1p; Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization [Source:SGD;Acc:S000000684] [Ensembl]

Observation:

ABP1 deletion increases replicative lifespan by 30% in the alpha strain and decreases replicative lifespan by 20% in the a strain [18340043]. Deletion of ABP1 increases replicative lifespan by 20% in the alpha strain and decreases replicative lifespan by 20% in the a strain [19030232].

Interventions:

ABP1 deletion -20 to +30%

Assays: Replicative Lifespan

Classification:

Aging Associated

Aging Relevance Analysis/Source:

GenAge